I don't know if tis has been mentioned before regarding drives larger than 750GB but I have a 4 port switch hooked up to my 722 and 3 Western Digital 750GB either Home or Premium MyBook drives and was going to add the fourth. Then I remembered I had a 1TB WD MyBook drive and though rather than buying another 750GB drive, I'd hook up that drive and see what would happen. The 722 at the time was running 5.12 and it saw the drive, offered to format it and after format there was 930GB of free space which was 1GB less than I had with the same drive under Vista Ultimate 64 with NTFS. So far the drive has been fine with transfer and playback and I wonder if a 2TB drive will work as well. My next step is to see if I can replace my 4 port switch with an 8 port model as there are plenty of HD movies and shows that I'd like to have around for awhile.