Just and update...
Ok, now running the TapaTalk fix (Which is what I think the overall issue was.) from 11:13 AM ET this morning. I have not seen anyone say things were still bad...so I think that was it.
However...What we did do was...
Upgraded MySQL to ver 5.5
Also have XCache running again. (Had stopped it just in case) XCache speeds up php code by caching the php scripts in a compiled format vs needing to compile it with each call. The entire site runs off PHP and MySQL
Also now running the Sphinx search engine. This is a very fast search solution vs MySQL standard search. Each morning at 4:00AM CT it will slow the site down as it reindexes for just a few mins. (Side note...new posts will be added to the search indexes within 10 mins of posting vs real time.)
So....Now let's see how this all goes.