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From Huffpost:
Actress Kathryn Joosten, best known as "Desperate Housewives'" most meddlesome neighbor Karen McKluskey, died Friday after a long battle with lung cancer. She was 72.
Joosten's death came less than three weeks after the emotional "Desperate Housewives" series finale, which saw the redemption and eventual death of Mrs. McKluskey as well.
Joosten won two Emmys for Outstanding Guest Actress in a Comedy Series for her "Desperate" role, in 2005 and 2008, and was nominated for a third time in 2010.
She also had memorable TV roles on "Scrubs," "Joan of Arcadia," "My Name Is Earl," "General Hospital" and "Dharma & Greg."