Can't speak from personal experience, however this seems to be a not uncommon problem... the suggestions that resolved it successfully included:
Updating the Flash Player.
Run the offending game in XP compatibility mode
Use msconfig to disable ALL start ups and start Vista clean, then reinstall the game.
Lots more... just Google Macromedia Projector has stopped working
Updating the Flash Player.
Run the offending game in XP compatibility mode
Use msconfig to disable ALL start ups and start Vista clean, then reinstall the game.
Lots more... just Google Macromedia Projector has stopped working